A new study reveals alarming findings at the 2025 EHRA congress. Long-term antidepressant use may significantly elevate the risk of sudden cardiac death (SCD), urging a deeper examination of mental health treatments and their cardiovascular effects.

Sudden cardiac death (SCD) strikes unexpectedly, often stemming from heart problems. Typically occurring within an hour of symptoms, it predominantly affects those with pre-existing heart conditions.

Research shows that individuals with psychiatric disorders face a higher mortality rate, including double the risk of SCD. This raises questions about how antidepressant treatments factor into overall cardiovascular health and SCD rates.

Analyzing records of nearly 644,000 antidepressant users against a backdrop of 4.3 million, the study uncovered critical insights. Prolonged use significantly raises SCD risks, particularly in younger populations.

Experts share mixed views on the findings. Dr. Keedwell emphasizes the dangerous implications of untreated depression, while others suggest the observed SCD risk may stem from pre-existing health issues rather than the medication alone.

The higher SCD risk identified in long-term antidepressant users highlights serious public health concerns.

These revelations demand further exploration into antidepressants and heart health.